Faculty

Martin Aryee

Aryee.martin@mgh.harvard.edu

Associate Professor of Pathology

We develop computational and statistical methods for extracting signal from noisy genomic datasets, with a focus on cancer epigenomics. Our group members' interests range from understanding the basic epigenetic mechanisms underlying human disease, to...

Paul Avillach

Paul_Avillach@hms.harvard.edu

Assistant Professor of Biomedical Informatics

The Avillach Lab, led by Paul Avillach, M.D., Ph.D., focuses on translational bioinformatics, specifically in integrating multiple heterogeneous sources of clinical and genomic data in a meaningful way. We are passionate about combining data across...

Sylvan Baca

sbaca@partners.org

Assistant Professor of Medicine

Our lab develops and applies computational methods in an emerging space we call “translational epigenomics”. This space encompasses efforts to advance precision oncology by deeply characterizing cancer epigenomes. By examining epigenetic changes in...

Michael Baym

baym@hms.harvard.edu

Assistant Professor of Biomedical Informatics

Our research crosses a broad spectrum of areas, centered around microbial evolutionary genomics and antibiotic resistance. Our projects are curiosity-driven and range from fundamental evolutionary questions, to genetic arms races, to algorithmic and...

Bonnie Berger

bab@mit.edu

Member of the Harvard-MIT Health Sciences and Technology Faculty

Bonnie Berger is a Professor of Applied Mathematics and Computer Science at MIT, and head of the Computation and Biology group at MIT's Computer Science and AI Lab. After beginning her career working in algorithms at MIT, she was one of the pioneer...

Rameen Beroukhim

rameen_beroukhim@dfci.harvard.edu

Associate Professor of Medicine

The Beroukhim laboratory focuses on understanding the somatic genetics of cancer, primarily in identifying alterations in chromosomal structure (including copy-number gains and losses and loss of heterozygosity) that contribute to tumor growth, and...

Jason Daniel Buenrostro

jason_buenrostro@harvard.edu

Assistant Professor of Stem Cell and Regenerative Biology

Our laboratory seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new technologies that integrate molecular biology, microscopy, and large-scale bioinformatics. These efforts include new methods...

Martha Leonia Bulyk

mlbulyk@genetics.med.harvard.edu

Professor of Medicine

Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The interactions between transcription factors (TFs) and their DNA binding sites are an integral part of the...

Tianxi Cai

tcai@hsph.harvard.edu

John Rock Professor of Population and Translational Data Sciences

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at...

Christopher Cassa

ccassa@hms.harvard.edu

Assistant Professor of Medicine

Our research group studies the statistical genetics of Mendelian disorders. We focus on two major application areas: methods to assess the pathogenicity of genomic variants and the clinical application of predictive algorithms in genomics. These...

Kaifu Chen

kaifu.chen@childrens.harvard.edu

Associate Professor of Pediatrics

We are a bioinformatics lab developing computation technology to model how cell identity is established during differentiation. We develop bioinformatics methods to understand genetic, epigenetic, and molecular signaling mechanisms in cell identity...

George Mcdonald Church

gchurch@genetics.med.harvard.edu

Robert Winthrop Professor of Genetics

Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in particular, personal genomics and biofuels. We have developed next-generation sequencing methods to analyze the...

Stirling Churchman

churchman@genetics.med.harvard.edu

Associate Professor of Genetics

Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven challenging, because most experimental approaches record downstream products fed by multiple pathways –...

Mark Joseph Daly

mjdaly@atgu.mgh.harvard.edu

Associate Professor of Medicine

Dr. Daly's lab focuses on computational approaches to understanding the genetics of disease with a strategy of integrating powerful techniques from human and mouse genetics. The lab has extensive experience in linkage and association analysis and has...

Felix Dietlein

felix.dietlein@childrens.harvard.edu

Assistant Professor of Pediatrics

Dr. Dietlein is an Assistant Professor at Harvard Medical School, an Associate Member of the Broad Institute, Core Faculty in the Computational Health Informatics Program at Boston Children’s Hospital, and an Investigator at the Dana-Farber Cancer...

Stephen J. Elledge

selledge@genetics.med.harvard.edu

Gregor Mendel Professor of Genetics and of Medicine

A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA damage, they induce the transcription of genes involved in cell cycle arrest and repair of the damage...

Maha Farhat

mrfarhat@partners.org

BIG Associate Director

Associate Professor of Biomedical Informatics

The Farhat lab is a translational lab that combines genomics and informatics to understand and better control drug resistant tuberculosis and other infections. We are particularly interested in bacterial genome wide association, prediction of phenotype...

Jason Flannick

flannick@broadinstitute.org

Assistant Professor of Pediatrics

The Flannick Lab develops computational approaches to use human genetics to understand or better treat human diseases, with a current focus on diabetes. We are based at Boston Children’s Hospital, Harvard Medical School, and the Broad Institute; perform...

Nils Gehlenborg

nils@hms.harvard.edu

Associate Professor of Biomedical Informatics

Nils Gehlenborg received his PhD from the University of Cambridge and was a predoctoral fellow at the European Bioinformatics Institute (EMBL-EBI). The goal of Gehlenborg's research is to improve human health by developing computational techniques and...

Gad Getz

gadgetz@broadinstitute.org

Professor of Pathology

Gad Getz directs the Cancer Genome Computational Analysis group at the Broad Institute of MIT and Harvard, where he is an institute member. Under Getz's leadership, the Cancer Genome Analysis group has established itself as a world leader in the...

Todd R. Golub

golub@broad.harvard.edu

Professor of Pediatrics

Todd Golub is a founding core member of the Broad Institute and serves as the institute director. Golub is a world leader in understanding the basis of cancer, by creating and applying tools of genomics. He has made fundamental discoveries in the...

Robert C. Green

rcgreen@bwh.harvard.edu

Professor of Medicine

Robert C. Green, MD, MPH is a medical geneticist and physician-scientist who directs the G2P Research Program in translational genomics and health outcomes in the Division of Genetics at Brigham and Women's Hospital and Harvard Medical School. Dr. Green...

Doga Gulhan

dgulhan@mgh.harvard.edu

Assistant Professor

Doga is the Principal Investigator of Gulhan Lab at Mass General Hospital (MGH) Cancer Center and an Assitant Professor of Medicine and Biomedical Informatics (Secondary) at Harvard Medical School (HMS). She received her Bachelor of Science degree from...

James Francis Gusella

gusella@helix.mgh.harvard.edu

Bullard Professor of Neurogenetics in the Department of Genetics

My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, management and...

Alexander Gusev

alexander_gusev@dfci.harvard.edu

Associate Professor of Medicine

We are quantitative geneticists working on methods to understand complex disease. Our research focuses on deciphering biological mechanisms and trait biology from genome-wide association studies; germline influences of cancer and response to therapy; and...

Steven P. Gygi

steven_gygi@hms.harvard.edu

Professor of Cell Biology

Technology drives biological research. A new technology can instantly provide answers that were difficult or impossible to address using current approaches. The emerging field of proteomics provides researchers an alternative/complementary strategy to the...

Nir Hacohen

nhacohen@mgh.harvard.edu

Professor of Medicine

The Hacohen lab consists of immunologists, geneticists, biochemists, technologists, physicians and computational biologists working together to develop new and unbiased technologies and strategies to understand basic immune processes and immune-mediated...

Kevin M. Haigis

kevin_haigis@dfci.harvard.edu

Professor of Medicine

Our laboratory studies diseases of the gastrointestinal tract, with emphasis on colorectal cancer (CRC) and inflammatory bowel disease (IBD). We use both conventional and systems biology approaches to integrate studies of genetically engineered mouse...

Joel Naom Hirschhorn

joel.hirschhorn@childrens.harvard.edu

Concordia Professor of Pediatrics

There are clear resemblances between parents and children for height, weight, and many other traits and diseases; these familial resemblances are influenced strongly by inherited genetic factors. Most common diseases (such as diabetes, obesity, or asthma)...

Hailiang Huang

hhuang@atgu.mgh.harvard.edu

Assistant Professor

The Huang Lab develops and applies cutting-edge statistical genetics and computational techniques to understand the genetic architecture of human complex disorders, especially autoimmune and psychiatric disorders. We are especially interested in novel...