The Xia lab seeks to address one of biology’s central questions: how does the human genome control the identity and function of thousands of cell types, and what goes wrong with the cells in conditions like aging and cancer? In our lab, we combine state...
Our lab is interested in studying the mechanisms of spatio-temporal tumor evolution, progression and therapy response. Our current research focuses on scalable inference methods and modeling of single-cell genomic and in situ imaging data to study the co...
I am principal investigator of the Korsunsky lab at Brigham and Women’s Hospital. I completed my PhD with Dr. Bud Mishra at NYU’s Courant Institute of Mathematical Sciences. I started my postdoctoral training in rheumatology with Dr. Peter Gregersen at...
Doga is the Principal Investigator of the Gulhan Lab at the Krantz Family Center for Cancer Research at Mass General Hospital (MGH) and an Assistant Professor of Medicine and of Biomedical Informatics (secondary) at Harvard Medical School (HMS). She...
Our lab develops and applies computational methods in an emerging space we call “translational epigenomics”. This space encompasses efforts to advance precision oncology by deeply characterizing cancer epigenomes. By examining epigenetic changes in...
We are a bioinformatics lab developing computation technology to model how cell identity is established during differentiation. We develop bioinformatics methods to understand genetic, epigenetic, and molecular signaling mechanisms in cell identity...
The Rheinbay laboratory concentrates on identifying and functionally characterizing non-coding drivers in the sequences of tumor genomes through development of novel analysis strategies and collaborations with experimental investigators.
Most known genomic...
The Lotter Lab performs interdisciplinary research with two core aims: 1) developing more robust computer vision algorithms using insights from human vision, and 2) optimizing these algorithms for medical imaging to deliver real-world impact. We aim to...
Dr. Dietlein is an Assistant Professor at Harvard Medical School, an Associate Member of the Broad Institute, Core Faculty in the Computational Health Informatics Program at Boston Children’s Hospital, and an Investigator at the Dana-Farber Cancer...
My laboratory studies chromosomal abnormalities in cancer. Examples of such alterations include aneuploidy, whole-genome duplication, and complex chromosomal rearrangements. Despite their prevalence, the origin and functional impact of these alterations...
