Statistical methods

Kaitlin Samocha is an Assistant Professor in the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School. She is on the steering committee for the Genome Aggregation Database (gnomAD), one of the world’s largest publicly...

Our group develops and applies efficient and accurate statistical methods and computational tools to understand the genetic/genomic basis of human disease risk and progression using large-scale biobanks. We also leverage high-dimensional omics data to...

We are a bioinformatics lab developing computation technology to model how cell identity is established during differentiation. We develop bioinformatics methods to understand genetic, epigenetic, and molecular signaling mechanisms in cell identity...

Data generated by the rapidly advancing DNA sequencing technology provide the complete picture of population genetic variation and sequence divergence between species. We have been focused on the analysis of systematic re-sequencing datasets with the...

I am an associate professor in the Program in Genetic Epidemiology and Statistical Genetics in the Department of Epidemiology at HSPH, with a secondary appointment in the Department of Biostatistics. I am an associate member of the Program in Medical and...

Rafael Irizarry received his Bachelor's in Mathematics in 1993 from the University of Puerto Rico and went on to receive a Ph.D. in Statistics in 1998 from the University of California, Berkeley. His thesis work was on Statistical Models for Music Sound...

We are quantitative geneticists working on methods to understand complex disease. Our research focuses on deciphering biological mechanisms and trait biology from genome-wide association studies; germline influences of cancer and response to therapy; and...

We develop computational and statistical methods for extracting signal from noisy genomic datasets, with a focus on cancer epigenomics. Our group members' interests range from understanding the basic epigenetic mechanisms underlying human disease, to...