The Xia lab seeks to address one of biology’s central questions: how does the human genome control the identity and function of thousands of cell types, and what goes wrong with the cells in conditions like aging and cancer? In our lab, we combine state...
Our group develops and applies efficient and accurate statistical methods and computational tools to understand the genetic/genomic basis of human disease risk and progression using large-scale biobanks. We also leverage high-dimensional omics data to...
Dongwon Lee’s laboratory aims to understand how gene regulation contributes to the development and progression of human diseases, specifically focusing on kidney diseases. We use a combination of single-cell multiomics data, genetic data from disease...
Genetic studies for a wide variety of traits and diseases have grown exponentially over the last decade, providing fine-scale biological insights into disease mechanisms. However, these genetic studies have been vastly Eurocentric in composition. We have...
Our laboratory utilizes human genetic approaches to gain insight into blood cell production (hematopoiesis) and how this process is perturbed in disease states. We study rare genetic blood disorders and the genetics underlying variation in hematopoiesis...
Research:
AI holds tremendous promise in enabling scientific breakthroughs and discoveries in diverse areas. Dr. Zitnik investigates machine learning with a current focus on networked systems that require infusing structure and domain knowledge. This...
