Work in the Seidman laboratory (Dept of Genetics, HMS) is directed toward identifying gene defects that cause inherited heart disease and defining the pathways by which these mutations mediate disease. We begin by using human genetic techniques to...
We develop computational tools to solve statistical and algorithmic challenges in quantitative genetics.
We are based in the Division of Genetics and Center for Data Sciences at Brigham and Women's Hospital / Harvard Medical School. We are affiliated...
Our laboratory utilizes human genetic approaches to gain insight into blood cell production (hematopoiesis) and how this process is perturbed in disease states. We study rare genetic blood disorders and the genetics underlying variation in hematopoiesis...
Using a combination of computational and experimental approaches we study the processes that determine whether mammalian cells live or die. Our lab is particularly interested in apoptosis triggered by extracellular ligands such as TRAIL, Fas and TNF and...
Our laboratory studies diseases of the gastrointestinal tract, with emphasis on colorectal cancer (CRC) and inflammatory bowel disease (IBD). We use both conventional and systems biology approaches to integrate studies of genetically engineered mouse...
