Faculty

Martin Aryee

Aryee.martin@mgh.harvard.edu

Associate Professor of Pathology

We develop computational and statistical methods for extracting signal from noisy genomic datasets, with a focus on cancer epigenomics. Our group members' interests range from understanding the basic epigenetic mechanisms underlying human disease, to...

Paul Avillach

Paul_Avillach@hms.harvard.edu

Assistant Professor of Biomedical Informatics

The Avillach Lab, led by Paul Avillach, M.D., Ph.D., focuses on translational bioinformatics, specifically in integrating multiple heterogeneous sources of clinical and genomic data in a meaningful way. We are passionate about combining data across...

Sylvan Baca

sbaca@partners.org

Assistant Professor of Medicine

Our lab develops and applies computational methods in an emerging space we call “translational epigenomics”. This space encompasses efforts to advance precision oncology by deeply characterizing cancer epigenomes. By examining epigenetic changes in...

Michael Baym

baym@hms.harvard.edu

Assistant Professor of Biomedical Informatics

Our research crosses a broad spectrum of areas, centered around microbial evolutionary genomics and antibiotic resistance. Our projects are curiosity-driven and range from fundamental evolutionary questions, to genetic arms races, to algorithmic and...

Bonnie Berger

bab@mit.edu

Member of the Harvard-MIT Health Sciences and Technology Faculty

Bonnie Berger is a Professor of Applied Mathematics and Computer Science at MIT, and head of the Computation and Biology group at MIT's Computer Science and AI Lab. After beginning her career working in algorithms at MIT, she was one of the pioneer...

Rameen Beroukhim

rameen_beroukhim@dfci.harvard.edu

Associate Professor of Medicine

The Beroukhim laboratory focuses on understanding the somatic genetics of cancer, primarily in identifying alterations in chromosomal structure (including copy-number gains and losses and loss of heterozygosity) that contribute to tumor growth, and...

Jason Daniel Buenrostro

jason_buenrostro@harvard.edu

Assistant Professor of Stem Cell and Regenerative Biology

Our laboratory seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new technologies that integrate molecular biology, microscopy, and large-scale bioinformatics. These efforts include new methods...

Martha Leonia Bulyk

mlbulyk@genetics.med.harvard.edu

Professor of Medicine

Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The interactions between transcription factors (TFs) and their DNA binding sites are an integral part of the...

Tianxi Cai

tcai@hsph.harvard.edu

John Rock Professor of Population and Translational Data Sciences

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at...

Christopher Cassa

ccassa@hms.harvard.edu

Assistant Professor of Medicine

Our research group studies the statistical genetics of Mendelian disorders. We focus on two major application areas: methods to assess the pathogenicity of genomic variants and the clinical application of predictive algorithms in genomics. These...

Kaifu Chen

kaifu.chen@childrens.harvard.edu

Associate Professor of Pediatrics

We are a bioinformatics lab developing computation technology to model how cell identity is established during differentiation. We develop bioinformatics methods to understand genetic, epigenetic, and molecular signaling mechanisms in cell identity...

George Mcdonald Church

gchurch@genetics.med.harvard.edu

Robert Winthrop Professor of Genetics

Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in particular, personal genomics and biofuels. We have developed next-generation sequencing methods to analyze the...