# Vijay G. Sankaran Jan Ellen Paradise, MD Professor of Pediatrics ![sankaran_vijay.jpg](/sites/g/files/omnuum6836/files/styles/hwp_4_5__480x600/public/bigphd/files/sankaran_vijay_0.jpg?itok=shwQQnhj) location\_on Boston Children's Hospital 1 Blackfan Circle, Karp Family Research Building 7211Boston, MA 02115 smartphone [617-919-6270](tel:617-919-6270) email laptop\_windows [Lab website](https://www.bloodgenes.org/) laptop\_windows [Publications](https://www.ncbi.nlm.nih.gov/pubmed/?term=sankaran+vg) Our laboratory utilizes human genetic approaches to gain insight into blood cell production (hematopoiesis) and how this process is perturbed in disease states. We study rare genetic blood disorders and the genetics underlying variation in hematopoiesis in large population-based studies. We also perform mechanistic functional studies in primary human hematopoietic cells to obtain a deeper understanding of hematopoiesis. We are particularly interested in gaining insight into the genetic basis of a variety of blood disorders, obtaining a deeper understanding of the developmental regulation of hemoglobin switching, and in developing tools that can be used for functional follow up of human genetic studies. - ## AIM or BIG Faculty [BIG Faculty](/aim-and-big-faculty/big-faculty) - ## Biological/Medical Focus [Immunology including autoimmune](/biologicalmedical-focus/immunology-including-autoimmune) [Complex disease](/biologicalmedical-focus/complex-disease) - ## Faculty research type [Hybrid of computational and experimental](/faculty-research-type/hybrid-computational-and-experimental) - ## Methodological Focus [Single cell profiling](/methodological-focus/single-cell-profiling) [Genome analysis](/methodological-focus/genome-analysis) - ## People [BIG Program Faculty](/people/BIGfaculty) - ## Primary affiliation [BCH](/primary-affiliation/bch) - ## Research Area [Human genetic studies of blood production](/research-area/human-genetic-studies-blood-production)