#  August Yue Huang 

Assistant Professor

 

 

 



   ![Yue (August) Huang](/sites/g/files/omnuum6836/files/styles/hwp_4_5__320x400/public/2026-10/Photo%20August.png?itok=AyeZCKmF) 

 



 

 email <yue.huang@childrens.harvard.edu> 

 laptop\_windows <https://www.augusthuanglab.org/> 

 

 



 

The Huang Lab pioneers computational approaches to characterize somatic mutations across diverse sequencing technologies and leverages these innovations to understand their impact on health and disease. Somatic mutations accumulate throughout development and aging in virtually all cell types, contributing to genomic diversity within individuals and playing important roles in a broad spectrum of human diseases. Through close collaborations with experimental scientists investigating diverse tissues and disease conditions, we integrate computational genomics with biological discovery to advance our understanding of somatic mutagenesis and its consequences for human health. Ultimately, our research aims to inform innovative strategies for disease prevention, diagnosis, and treatment.





 

 

 





 

 

- ## AIM or BIG Faculty
    
     [BIG Faculty](/aim-and-big-faculty/big-faculty)
- ## Biological/Medical Focus
    
     [Aging/neurodegeneration](/biologicalmedical-focus/agingneurodegeneration) [Neurodevelopment](/biologicalmedical-focus/neurodevelopment) [Genetics of human disease](/biologicalmedical-focus/genetics-human-disease) [Cardiovascular disease](/biologicalmedical-focus/cardiovascular-disease)
- ## Faculty research type
    
     [Computational](/faculty-research-type/computational)
- ## Methodological Focus
    
     [Single cell profiling](/methodological-focus/single-cell-profiling) [Genome analysis](/methodological-focus/genome-analysis) [ML/AI](/methodological-focus/mlai)
- ## People
    
     [BIG Program Faculty](/people/BIGfaculty)
- ## Primary affiliation
    
     [BCH](/primary-affiliation/bch)
- ## Year Entered BIG Program
    
     [2026](/year-entered-program/2026)